Placental inflammation and autism?

The placenta . Quite an important part of the nine months that makes us; an organ exquisitely evolved to provide oxygen and nutrition to the...

autismbirthinflammationmaternal immune activation (MIA)placentarisk

"a leaky gut may play a critical role in the development of age-related inflammation and frailty"

The quote heading this post is taken from the findings reported by Yanfei Qi and colleagues [1] who set out to investigate whether " a...

ageagingexercisegastrointestinalinflammationleaky gutzonulin

Schizophrenia and CRP meta-analysed again

" Our study provides evidence that higher CRP  [ C-reactive protein ]  levels are associated with increased risk of SZ  [ schizophrenia...

C-reactive protein (CRP)immune systeminflammationmeta-analysisschizophrenia

Oral vitamin D and the inflammatory effects of sunburn

In something of a departure from the typical content of this blog, I want to briefly introduce the paper by Jeffrey Scott and colleagues [1...

immune systeminflammationskinsunburnsunshinevitamin d

The inflammatory effects of unemployment?

" Our study demonstrates that systemic inflammation is associated with an important but little-studied aspect of the social environmen...

C-reactive protein (CRP)employmentimmune systeminflammationmedicalmeta-analysisrisk

Autism, pregnancy maternal immune activation and vitamin D?

Today's post is a bit of a mash-up, drawing on two articles quite recently published in the peer-reviewed science domain. The first is b...

autismbehaviourdevelopmentgeneticsinflammationmaternal immune activation (MIA)offspringpregnancyrodentssupplementationvitamin d

HSV-2 gestational infection and offspring autism risk

" In our cohort, high levels of antibodies to herpes simplex virus 2 at midpregnancy were associated with an elevated risk of autism s...

autismcytomegalovirus (CMV)Herpes Simplex virusimmune systeminflammationmaternal immune activation (MIA)pregnancyrubellaviral

New Video on Sinusitis and Sinus Surgery Explained (Balloon Sinuplasty and Endoscopic Sinus Surgery)

A  new video  has been uploaded to YouTube that explains how sinus infections occur as well as how sinus surgery helps with this condition ...

balloon sinuplastyballoon sinus surgerychronic sinus infectionschronic sinusitisendoscopic sinus surgeryinfectioninflammationrecurrent sinusitissinussinusitissurgerytreatmentvideo

Maternal pregnancy CRP levels and offspring autistic traits

Elevated levels of inflammatory markers present during pregnancy have been linked to quite a few labels and diagnoses down the years. Schizo...

autismC-reactive protein (CRP)immune systeminflammationmaternalpregnancyschizophreniatraits

Theory of mind and major depressive disorder

Today I'm briefly serving up the paper by Emre Bora & Michael Berk [1] for your daily reading and the results of their meta-analysi...

autismcomorbiditydepressioninflammationtheory of mind

Does eczema increase the risk of childhood speech disorder?

Nativity Kylo? The question posed in the title of this post reflects some interesting data published by Mark Strom & Jonathan Silverberg...

eczemaimmune systeminflammationriskskinspeech

Schizophrenia and the constant (immune) gardeners

" Immune clue to preventing schizophrenia " went the BBC headline, as the paper by Peter Bloomfield and colleagues [1] garnered s...

anti-inflammatorybrainimmune systeminflammationinterventionmacrophagemicrogliaschizophreniathe schizophrenias

Immunosuppression as a therapeutic pathway of clozapine?

" Our data suggest that the superior therapeutic effect of clozapine may be a result of its presently shown immunosuppressive action. ...

anti-inflammatoryclozapinecytokinesimmune systeminflammationinterleukin-8 (IL-8)kynurenic acidratsschizophreniathe schizophrenias

Autism, luteolin and inflammatory markers

" We further show that the children with ASDs  [autism spectrum disorders]  in which the elevated serum IL-6 and TNF levels decreased...

autismbrain-derived neurotrophic factor (BDNF)cytokinesinflammationinterleukin-6 (IL-6)luteolinsupplementationTNF-alpha

The neuropathology linking T. gondii infection and schizophrenia?

A quote to begin: " findings suggest that T gondii  [ Toxoplasma gondii ]  infection causes substantial and widespread immune activatio...

brainC-reactive protein (CRP)immune systeminfectioninflammationmouseschizophreniaToxoplasma gondii