Mitochondrial mutations are not common in chronic fatigue syndrome but...

" We report the complete mtDNA [ mitochondrial DNA ]  sequence of 93 CFS  [ chronic fatigue syndrome ]  patients from the UK and RSA , ...

Chronic fatigue syndrome (CFS)fatiguegeneticsinterventionmitochondrial disorderscreening

Mitochondria support for mitochondrial activity in [some] autism

" This study examined the effect of common mitochondrial treatments on specific mitochondrial components in a group of children diagnos...

autismcarnitinecoenzyme Q10fatty acidsfolateinterventionmitochondrial disorderscreening

Fatigue in adults with a 22q11.2 deletion syndrome

The genetic condition called  22q11.2 deletion syndrome (22q11.2DS) has, on occasion, provided some research fodder for this blog ( see her...

depressionfatiguemitochondrial disorderquality of lifescreening

Low muscle tone and autistic traits

" This large study showed a prospective association of infant muscle tone with autistic traits in childhood. " So said the finding...

autismconnective tissueEhlers-Danlos syndrome (EDS)hypotoniamitochondrial disordermuscle tonescreeningSRStraits

A high index of suspicion for mitochondrial disease in autism?

The paper by Bradley Brown & Theodore Rais [1] (open-access available here ) lies at the centre of today's brief musings and yet an...

assessmentautismdepressioninterventionmaternalmitochondrial disorderneurocardiogenic syncopeself injurious behaviour (SIB)

KPAX002 for Chronic Fatigue Syndrome?

My attention was grabbed recently by the paper published by Jon Kaiser [1] ( open-access available here ) detailing the results of a 'p...

carnitineChronic fatigue syndrome (CFS)fatigueKPAX002Methylphenidatemitochondrial disorderN-Acetylcysteine (NAC)pilot study

Vaccines not associated with autism: a meta-analysis

I'm gonna warn you that this is probably the longest of my ramblings so far covering one of the most controversial topics linked to auti...

antibodiesautismautoimmunitycorrelationgastrointestinalmercurymitochondrial disorderparacetamolriskVaccine

Oxidative stress inducing mitochondrial dysfunction in autism?

Consider this post a sort of accompaniment to my recent chatter about the paper by Suzanne Goh and colleagues on brain lactate levels and mi...

autismglutathionelymphoblastoid cell lines (LCLs)mitochondrial disorderN-Acetylcysteine (NAC)oxidative stressphenotypes

Mitochondrial dysfunction as a neurobiological subtype of autism

The paper by Suzanne Goh and colleagues [1] reporting on " a possible neurobiological subtype of mitochondrial dysfunction in ASD  [au...

autismbrainlactatelactic acidosismitochondrial disorder

Chronic Fatigue Syndrome and various factors

The paper by Kate Lievesley and colleagues  [1] documenting various " predisposing, precipitating and perpetuating factors in Chronic F...

antiviralbehaviourCBTChronic fatigue syndrome (CFS)epigeneticsgeneticsimmune systeminfectionmitochondrial disordermyalgic encephalomyelitis (ME)risk